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Ter Arkh ; 93(9): 1132-1137, 2021 Sep 15.
Article in Russian | MEDLINE | ID: covidwho-1486854

ABSTRACT

Mineralocorticoid receptor antagonists have been successfully used for many years to treat patients with primary hyperaldosteronism, refractory arterial hypertension and chronic heart failure. The increased interest in this drug in recent years is due to new information about its antifibrotic and antiproliferative effects, both cardiac and extracardiac. The article also discusses the possibility of using spironolactone in patients with the new coronavirus infection SARS-CoV-2 (COVID-19).


Subject(s)
COVID-19 Drug Treatment , Hypertension , Humans , Mineralocorticoid Receptor Antagonists/pharmacology , Mineralocorticoid Receptor Antagonists/therapeutic use , Spironolactone/pharmacology , Spironolactone/therapeutic use , Eplerenone/therapeutic use , Aldosterone , SARS-CoV-2 , Hypertension/drug therapy
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